About our research
It may seem simple, but even an action like reaching for a cup of coffee requires complex and instantaneous computations by the brain. Cognitive factors, such as memories of using similar cups in the past can influence these computations. Mental health also plays a role—for example, how much we value drinking the coffee can affect how we reach for the cup.
Our research aims to understand the links between cognition, mental health, and action, both in health and disease. We combine computational methods with physiological measures and neuroimaging to investigate the mechanisms underlying these connections.
Current Projects
Transdiagnostic approach to human motivation: how do people perceive effort?
Changes in motivation are common in many neurological and psychiatric conditions, such as dementia and depression, but also in healthy individuals and in normal ageing. We attempt to understand the core mechanisms explaining individual differences in motivation. Our current project looks at how people perceive effort. To study this, we use a set of neurophysiological measures in tasks requiring physical and/or cognitive effort.
This project is funded by Israel Science Foundation (ISF).
Characterising Negative Symptoms in Schizophrenia
We investigate the processes underlying the cluster of symptoms called 'negative symptoms' in schizophrenia. These symptoms include reduced motivation or 'apathy' and reduced emotional expressivity. Although they tend to be overlooked and far less studied than 'positive symptoms' of hallucinations and delusions, negative symptoms determine long-term clinical outcome in patients.
In this project, we ask what leads to apathy in patients, and how this can be potentially treated. To investigate this, we use computerised tasks that ask participants to decide whether and which actions to perform under different experimental conditions.
This project is done in collaboration with Emilio Fernandez at the University of Cambridge.
Belief updating and learning to adapt to environmental changes
We look at how individual differences in mental health and age affect how people update their beliefs about the environment. Specifically, we examine how people adapt their behaviour in different contexts, and whether there is a common construct shared by belief updating tasks. We investigate whether changes in belief updating may put an individual at risk of mental health conditions, such as delusions and negative symptoms.
This project done is in collaboration with Matt Nassar at Brown University.
