List of publications from the lab

Wolpe N, Wu CL, Aymerich C, et al. (2026). Reduced option generation reveals distinct profiles of apathy in schizophrenia. medRxiv [link to preprint]

Schwarz N, Harlev D, Wolpe N (2026). Menstrual cycle selectively elevates anticipatory effort cost without altering reward sensitivity in human motivation. bioRxiv [link to preprint]

Jaeschke DC, Fradkin I, Wolpe N (2026). State rumination disrupts working memory and increases cognitive effort through cognitive interference. PsyArXiv [link to preprint]

Navarro V, Brugger S, Wolpe N, Harding J, Fletcher P, Teufel C (2026). Delusions emerge from generative model reorganisation rather than faulty inference: Insights from hybrid predictive coding. bioRxiv [link to preprint]

Harlev D, Hoffman R, Schwarz N, Halperin I, Wolpe N (2026). Fluctuations in emotional valence and arousal are differentially linked to cognitive performance and subjective mental effort. Emotion [link to full study]

Harlev D, Ravona-Springer R, Koren O, Zorani S, Plotnik M, Wolpe N (2026). Measuring apathy through computational lenses: Behavioral and physiological signatures of engagement in virtual reality. The American Journal of Geriatric Psychiatry [link to full study]

Demetriou I, Attaheri A, Bingham T, et al. (2026). The Cambridge Centre for Ageing and Neuroscience (Cam-CAN) longitudinal study protocol: Phase 4 (“Enrichment”) and Phase 5 (“Rescan”). Exploration of Neuroscience [link to full study]

Herzberg E, Halperin I, Wolpe N (2026). The cognitive and motor determinants of the perception of effort. Cognitive, Affective, & Behavioral Neuroscience [link to full study]

Xiao B, Wolpe N (2026). The value of progress feedback in physical effort-based decision making. Motivation Science [link to full study]

Schwarz N, Harlev D, Bergmann E, Wolpe N (2026). When the clock shifts: Menopause timing is associated with reduced cognitive performance and gray matter volume in a population-based cohort. Menopause [link to full study]

Harlev D, Vituri A, Shahar M, Wolpe N (2026). From dysphoria to anhedonia: Age-related shift in the link between cognitive and affective symptoms. The Journals of Gerontology, Series B: Psychological Sciences and Social Sciences [link to full study]

Wolpe N, Aymerich C, Jin Y, et al. (2025). Characterising Negative Symptoms in Schizophrenia: CHANSS study protocol. BJPsych Open [link to full study]

Fernandez-Egea et al. (2025). Assessment of motivation in schizophrenia: Patient- and clinician-rated outcomes. Spanish Journal of Psychiatry and Mental Health [link to full study]

Wolpe N, Harlev D, Bergmann E, Henson R (2025). Age-related positivity bias in emotion recognition is linked to lower cognitive performance and altered amygdala-orbitofrontal connectivity. Journal of Neuroscience [link to full study]

Harlev D, Vituri A, Shahar M, Wolpe N (2025). Depression and anxiety symptom networks across the lifespan. Age and Ageing [link to full study]

Wolpe N, Scott D, Salomon M, Nassar M, Fletcher P, Fernandez E (2025). Ageing is associated with exaggerated overstaying in foraging behaviour. npj Aging [link to full study]

Nagrodzki J, Passamonti L, Schweizer S, Stretton J, Knights E, Henson R, Wolpe N (2025). Behavioural and brain differences in the processing of negative emotion in previously depressed individuals: An exploratory analysis of population-based data. Emotion [link to full study]

Bergmann E, Harlev D, Wolpe N (2025). Depressive symptoms are linked to age-specific neuroanatomical and cognitive variations. Journal of Affective Disorders [link to full study]

Harlev D, Singer S, Goldshalger M, Wolpe N, Bergmann E (2025). Acoustic speech features are associated with late-life depression and apathy symptoms: Preliminary findings. Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring [link to full study]

Wolpe et al. (2025). Measuring the clinical dimensions of negative symptoms through the Positive and Negative Syndrome Scale. European Neuropsychopharmacology [link to full study]

Wolpe N, Holton R, Fletcher PC (2024). What is mental effort: a clinical perspective. Biological Psychiatry, Volume 95, Issue 11, 1030-1037. [link to full study]

Harding J, Wolpe N, Brugger SP, Navarro V, Teufel C, Fletcher PC (2024). A new predictive coding model for a more comprehensive account of delusions. The Lancet Psychiatry, Volume 11, Issue 4, 295 - 302. [link to full study]

Wolpe N, Vituri A, Jones PB, Shahar M, Fernandez-Egea E (2024). The longitudinal structure of negative symptoms in treatment resistant schizophrenia. Comprehensive Psychiatry, Volume 128. [link to full study]

Wolpe N, Fernandez-Egea E (2023). The structural stability of negative symptoms over time. BJPsych Open. 9:e208. [link to full study]

Wolpe N, Chen S, Kirkpatrick B, Jones PB, Jenkins C, Cardinal RN, Fernandez-Egea E (2023). Longitudinal effect of clozapine-associated sedation on motivation in schizophrenia: Naturalistic longitudinal study. The British Journal of Psychiatry. 223:295-297. [link to full study]

King DLO, Henson RN, Kievit R, Wolpe N, Brayne C, Tyler LK, Rowe JB; Cam-CAN; Tsvetanov KA (2023). Distinct components of cardiovascular health are linked with age-related differences in cognitive abilities. Scientific Reports 13:978. [link to full study]

Wolpe N, Hezemans FH, Rae CL, Zhang J, Rowe JB. The pre-supplementary motor area achieves inhibitory control by modulating response thresholds. Cortex. 152:98-108. [link to full study]

Fernandez-Egea E, Wolpe N. Is it time to change the term negative symptoms? European Neuropsychopharmacology. 59:7-8. [link to full study]

Hezemans FH, Wolpe N, O'Callaghan C, Ye R, Rua C, Jones PS, Murley AG, Holland N, Regenthal R, Tsvetanov KA, Barker RA, Williams-Gray CH, Robbins TW, Passamonti L, Rowe JB. Noradrenergic deficits contribute to apathy in Parkinson's disease through the precision of expected outcomes. PLoS Computational Biology. 18:e1010079. [link to full study]

Tomassini A, Hezemans FH, Ye R, Tsvetanov KA, Wolpe N, Rowe JB. Prefrontal Cortical Connectivity Mediates Locus Coeruleus Noradrenergic Regulation of Inhibitory Control in Older Adults. Journal of Neuroscience. 42:3484-3493. [link to full study]

O'Callaghan C, Hezemans FH, Ye R, Rua C, Jones PS, Murley AG, Holland N, Regenthal R, Tsvetanov KA, Wolpe N, Barker RA, Williams-Gray CH, Robbins TW, Passamonti L, Rowe JB. Locus coeruleus integrity and the effect of atomoxetine on response inhibition in Parkinson's disease. Brain. 144:2513-2526. [link to full study]

Wolpe N, Hezemans FH, Rowe JB (2020). Alien limb syndrome: A Bayesian account of unwanted actions. Cortex 127: 29-41. [link to full study]

Lewis-Smith D, Wolpe N*, Gosh BCP, Rowe JB (2020). Alien limb in the corticobasal syndrome: phenomenological characteristics and relationship to apraxia. *Joint first author. Journal of Neurology. 267: 1147–1157. [link to full study]

Hezemans FH, Wolpe N, Rowe JB (2020). Apathy is associated with reduced precision of prior beliefs about action outcomes. Journal of Experimental Psychology: General. 149: 1767-1777. [link to full study]

Wolpe N, Ingram JN, Tsvetanov K, Henson RN, Wolpert DM, Cam-CAN, Rowe JB (2020). Age-related reduction in motor adaptation: brain structural correlates and the role of explicit memory. Neurobiology of Ageing. 90: 13-23. [link to full study]

Wolpe N, Zhang Z, Nombela C, Ingram JN, Cam-CAN, Wolpert DM, Rowe JB (2018). Sensory attenuation in Parkinson’s disease is related to disease severity and dopamine dose. Scientific Reports 8: 15643. [link to full study]

Tsvetanov K, Ye Z, Hughes L, Samu D, Treder M, Wolpe N, Tyler LK, Cam-CAN, Rowe JB (2018). Activity and connectivity differences underlying inhibitory control across the adult lifespan. Journal of Neuroscience 38: 7887-7900. [link to full study]

Wolpe N, Ingram JN, Tsvetanov K, Geerligs L, Kievit RA, Henson RN, Wolpert DM, Cam-CAN, Rowe JB (2016). Ageing increases reliance on sensorimotor prediction through structural and functional differences in frontostriatal circuits. Nature Communications 7: 13034. [link to full study]

Zhang Z, Nombela C, Wolpe N, Barker RA, Rowe JB (2016). Time on timing: Dissociating premature responding from interval sensitivity in Parkinson's disease. Movement Disorders 31: 1163-1172. [link to full study]

Wolpe N, Nombela C, Rowe JB (2015). Dopaminergic modulation of positive expectations for goal-directed action: evidence from Parkinson’s disease. Frontiers in Psychology 6: 1514. [link to full study]

Wolpe N, Moore JW, Rae CL, Rittman T, Altena E, Haggard P, Rowe JB (2014). The medial frontal-prefrontal network for altered awareness and control of action in corticobasal syndrome. Brain 137: 208-220. [link to full study]

Wolpe N, Rowe JB (2014). Beyond the “urge to move”: objective measures for the study of agency in the post-Libet era. Frontiers in Human Neuroscience 8: 450. [link to full study]

Wolpe N, Wolpert DM, Rowe JB (2014). Seeing what you want to see: priors for one’s own actions represent exaggerated expectations of success. Frontiers in Behavioral Neuroscience 8: 232. [link to full study]

Wolpe N, Haggard P, Siebner HR, Rowe JB (2013). Cue integration and the perception of action in intentional binding. Experimental Brain Research 229: 467-474. [link to full study]

Galli G, Wolpe N, Otten LJ (2011). Sex differences in the use of anticipatory brain activity to encode emotional events. Journal of Neuroscience 31: 12364-12370. [link to full study]